The human homolog of Escherichia coli endonuclease V is a nucleolar protein with affinity for branched DNA structures.

Loss of amino groups from adenines in DNA results in the formation of hypoxanthine (Hx) bases with miscoding properties. The primary enzyme in Escherichia coli for DNA repair initiation at deaminated adenine is endonuclease V (endoV), encoded by the nfi gene, which cleaves the second phosphodiester...

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Autors principals:	Cathrine Fladeby, Erik Sebastian Vik, Jon K Laerdahl, Christine Gran Neurauter, Julie E Heggelund, Eirik Thorgaard, Pernille Strøm-Andersen, Magnar Bjørås, Bjørn Dalhus, Ingrun Alseth
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2012-01-01
Col·lecció:	PLoS ONE
Accés en línia:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23139746/pdf/?tool=EBI
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