The human homolog of Escherichia coli endonuclease V is a nucleolar protein with affinity for branched DNA structures.
Loss of amino groups from adenines in DNA results in the formation of hypoxanthine (Hx) bases with miscoding properties. The primary enzyme in Escherichia coli for DNA repair initiation at deaminated adenine is endonuclease V (endoV), encoded by the nfi gene, which cleaves the second phosphodiester...
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| Автори: | , , , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Public Library of Science (PLoS)
2012-01-01
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| Серія: | PLoS ONE |
| Онлайн доступ: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23139746/pdf/?tool=EBI |
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