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Construction of VSVΔ51M oncolytic virus expressing human interleukin-12

The use of oncolytic viruses (OVs) in combination with cytokines, such as IL-12, is a promising approach for cancer treatment that addresses the limitations of current standard treatments and traditional cancer immunotherapies. IL-12, a proinflammatory cytokine, triggers intracellular signaling path...

Deskribapen osoa

Gorde:
Egile Nagusiak: Rwaa H. Abdulal, Jana S. Malki, Ezdehar Ghazal, Ahdab A. Alsaieedi, Sarah A. Almahboub, Muhammad Yasir Khan, Reem M. Alsulaiman, Mazen M. Ghaith, Turki S. Abujamel, Magdah Ganash, Ahmad Bakur Mahmoud, Almohanad A. Alkayyal, Anwar M. Hashem
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2023-05-01
Saila:Frontiers in Molecular Biosciences
Gaiak:
oncolytic virus
VSVΔ51M
interleukin-12
cancer immunotherapy
B16F10
MCF-7
Sarrera elektronikoa:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1190669/full
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