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Construction of VSVΔ51M oncolytic virus expressing human interleukin-12

The use of oncolytic viruses (OVs) in combination with cytokines, such as IL-12, is a promising approach for cancer treatment that addresses the limitations of current standard treatments and traditional cancer immunotherapies. IL-12, a proinflammatory cytokine, triggers intracellular signaling path...

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Autori principali: Rwaa H. Abdulal, Jana S. Malki, Ezdehar Ghazal, Ahdab A. Alsaieedi, Sarah A. Almahboub, Muhammad Yasir Khan, Reem M. Alsulaiman, Mazen M. Ghaith, Turki S. Abujamel, Magdah Ganash, Ahmad Bakur Mahmoud, Almohanad A. Alkayyal, Anwar M. Hashem
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2023-05-01
Serie:Frontiers in Molecular Biosciences
Soggetti:
oncolytic virus
VSVΔ51M
interleukin-12
cancer immunotherapy
B16F10
MCF-7
Accesso online:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1190669/full
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