Chemotherapy increases CDA expression and sensitizes malignant pleural mesothelioma cells to capecitabine treatment

Abstract The combination of cisplatin and pemetrexed remains the gold standard chemotherapy for malignant pleural mesothelioma (MPM), although resistance and poor response pose a significant challenge. Cytidine deaminase (CDA) is a key enzyme in the nucleotide salvage pathway and is involved in the...

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書誌詳細

主要な著者:	Darya Karatkevich, Tereza Losmanova, Philipp Zens, Haibin Deng, Christelle Dubey, Tuo Zhang, Corsin Casty, Yanyun Gao, Christina Neppl, Sabina Berezowska, Wenxiang Wang, Ren-Wang Peng, Ralph Alexander Schmid, Patrick Dorn, Thomas Michael Marti
フォーマット:	Artigo
言語:	Inglês
出版事項:	Nature Portfolio 2024-08-01
シリーズ:	Scientific Reports
主題:	Chemotherapy Cisplatin Pemetrexed Capecitabine Cytidine deaminase Mesothelioma
オンライン･アクセス:	https://doi.org/10.1038/s41598-024-69347-x
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