Chemotherapy increases CDA expression and sensitizes malignant pleural mesothelioma cells to capecitabine treatment

Abstract The combination of cisplatin and pemetrexed remains the gold standard chemotherapy for malignant pleural mesothelioma (MPM), although resistance and poor response pose a significant challenge. Cytidine deaminase (CDA) is a key enzyme in the nucleotide salvage pathway and is involved in the...

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Bibliografiske detaljer

Principais autores:	Darya Karatkevich, Tereza Losmanova, Philipp Zens, Haibin Deng, Christelle Dubey, Tuo Zhang, Corsin Casty, Yanyun Gao, Christina Neppl, Sabina Berezowska, Wenxiang Wang, Ren-Wang Peng, Ralph Alexander Schmid, Patrick Dorn, Thomas Michael Marti
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Portfolio 2024-08-01
Serier:	Scientific Reports
Fag:	Chemotherapy Cisplatin Pemetrexed Capecitabine Cytidine deaminase Mesothelioma
Online adgang:	https://doi.org/10.1038/s41598-024-69347-x
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