Characterization of Shy1, the Schizosaccharomyces pombe homolog of human SURF1

Abstract Cytochrome c oxidase (complex IV) is the terminal enzyme in the mitochondrial respiratory chain. As a rare neurometabolic disorder caused by mutations in the human complex IV assembly factor SURF1, Leigh Syndrome (LS) is associated with complex IV deficiency. In this study, we comprehensive...

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Autors principals:	Ying Luo, Yuanqi Xu, Fawad Ahmad, Gang Feng, Ying Huang
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2024-09-01
Col·lecció:	Scientific Reports
Matèries:	Schizosaccharomyces pombe mitochondria cytochrome c oxidase Shy1 SURF1
Accés en línia:	https://doi.org/10.1038/s41598-024-72681-9
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