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Characterization of Shy1, the Schizosaccharomyces pombe homolog of human SURF1

Abstract Cytochrome c oxidase (complex IV) is the terminal enzyme in the mitochondrial respiratory chain. As a rare neurometabolic disorder caused by mutations in the human complex IV assembly factor SURF1, Leigh Syndrome (LS) is associated with complex IV deficiency. In this study, we comprehensive...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Ying Luo, Yuanqi Xu, Fawad Ahmad, Gang Feng, Ying Huang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2024-09-01
Schriftenreihe:Scientific Reports
Schlagworte:
Schizosaccharomyces pombe
mitochondria
cytochrome c oxidase
Shy1
SURF1
Online-Zugang:https://doi.org/10.1038/s41598-024-72681-9
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