Multivariate analysis of FcR-mediated NK cell functions identifies unique clustering among humans and rhesus macaques

Rhesus macaques (RMs) are a common pre-clinical model used to test HIV vaccine efficacy and passive immunization strategies. Yet, it remains unclear to what extent the Fc-Fc receptor (FcR) interactions impacting antiviral activities of antibodies in RMs recapitulate those in humans. Here, we evaluat...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Marina Tuyishime, Rachel L. Spreng, Brady Hueber, Junsuke Nohara, Derrick Goodman, Cliburn Chan, Richard Barfield, Whitney E. Beck, Shalini Jha, Stephanie Asdell, Kevin Wiehe, Max M. He, David Easterhoff, Haleigh E. Conley, Taylor Hoxie, Thaddeus Gurley, Caroline Jones, Nihar Deb Adhikary, Francois Villinger, Rasmi Thomas, Thomas N. Denny, Michael Anthony Moody, Georgia D. Tomaras, Justin Pollara, R. Keith Reeves, Guido Ferrari
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2023-12-01
Edice:	Frontiers in Immunology
Témata:	NK cells ADCC Fc gamma receptor antibody FcR-mediated effector functions rhesus macaques
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1260377/full
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!