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FcγR-driven chimeric receptor T cells in cancer therapy: a novel frontier in antibody-guided immunotherapy

Abstract This review article looks at a novel and flexible framework in adaptive cell treatment that enhances tumor targeting using Fc gamma receptor (FcγR)-based chimeric receptors. Though chimeric antigen receptor (CAR) T cell therapies have shown notable effectiveness in hematologic malignancies,...

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Autori principali: Hany E. Marei, Giacomo Pozzoli, Sara Caratelli, Carlo Cenciarelli
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2026-04-01
Serie:Cancer Cell International
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Accesso online:https://doi.org/10.1186/s12935-026-04258-7
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