TREM-1 inhibitor specificity and timing of treatment initiation can impact its therapeutic efficacy in cancer and inflammatory disease

BackgroundTriggering receptor expressed on myeloid cells 1 (TREM-1) is a key regulator in inflammation and an emerging therapeutic target in oncology and inflammatory disease.ObjectiveThis study aims to determine whether broad or macrophage-specific TREM-1 blockade demonstrates distinct therapeutic...

全面介绍

书目详细资料

主要作者:	Alexander B. Sigalov
格式:	Artigo
语言:	Inglês
出版:	Frontiers Media S.A. 2025-12-01
丛编:	Frontiers in Oncology
主题:	TREM-1 inhibitory SCHOOL peptides pan-TREM-1 blockade macrophage-restricted TREM-1 blockade resolution of inflammation cancer therapy-induced inflammation acute and chronic inflammation diseases
在线阅读:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1689771/full
标签:	添加标签 没有标签, 成为第一个标记此记录!