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Autophagic and endo-lysosomal dysfunction in neurodegenerative disease

Abstract Due to their post-mitotic state, metabolic demands and often large polarised morphology, the function and survival of neurons is dependent on an efficient cellular waste clearance system both for generation of materials for metabolic processes and removal of toxic components. It is not surp...

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Bibliografische Detailangaben
Hauptverfasser: Bilal R. Malik, Daniel C. Maddison, Gaynor A. Smith, Owen M. Peters
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2019-11-01
Schriftenreihe:Molecular Brain
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Online-Zugang:https://doi.org/10.1186/s13041-019-0504-x
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