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Physicochemical and Biochemical Evaluation of Amorphous Solid Dispersion of Naringenin Prepared Using Hot-Melt Extrusion

Naringenin (NRG) is a plant-derived flavonoid. Due to its antioxidant, anti-inflammatory, and analgesic activities it is beneficial to human health and is often used as a functional food ingredient; however, it has poor water solubility and low in vivo bioavailability. Therefore, the efficacy of NRG...

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Uloženo v:
Hlavní autoři: Kenji Ishimoto, Yukiko Shimada, Akane Ohno, Shuichi Otani, Yukio Ago, Soya Maeda, Bangzhong Lin, Kazuto Nunomura, Nobumasa Hino, Masayuki Suzuki, Shinsaku Nakagawa
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2022-04-01
Edice:Frontiers in Nutrition
Témata:
amorphous solid dispersion
analgesia
functional food
gastrointestinal absorption
hot-melt extrusion
naringenin
On-line přístup:https://www.frontiersin.org/articles/10.3389/fnut.2022.850103/full
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