JAK2 Inhibition by Fedratinib Reduces Osteoblast Differentiation and Mineralisation of Human Mesenchymal Stem Cells

Several signalling pathways, including the JAK/STAT signalling pathway, have been identified to regulate the differentiation of human bone marrow skeletal (mesenchymal) stem cells (hBMSCs) into bone-forming osteoblasts. Members of the JAK family mediate the intracellular signalling of various of cyt...

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Auteurs principaux:	Nihal AlMuraikhi, Hanouf Alaskar, Sarah Binhamdan, Amal Alotaibi, Moustapha Kassem, Musaad Alfayez
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2021-01-01
Collection:	Molecules
Sujets:	JAK/STAT signalling pathway JAK2 inhibition Fedratinib hMSC-TERT osteoblast differentiation in vitro mineralisation
Accès en ligne:	https://www.mdpi.com/1420-3049/26/3/606
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