Flow cytometry detection of cell type-specific expression of programmed death receptor ligand-1 (PD-L1) in colorectal cancer specimens

Aim: PD-1/PD-L1 blockade therapy is now widely used for the treatment of advanced malignancies. Although PD-L1 is known to be expressed by various host cells as well as tumor cells, the role of PD-L1 on non-malignant cells and its clinical significance is unknown. We evaluated cell type-specific exp...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Akira Saito, Mineyuki Tojo, Yuko Kumagai, Hideyuki Ohzawa, Hironori Yamaguchi, Hideyo Miyato, Ai Sadatomo, Daishi Naoi, Gaku Ota, Koji Koinuma, Hisanaga Horie, Alan Kawarai Lefor, Naohiro Sata, Joji Kitayama
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2021-01-01
coleção:	Heliyon
Assuntos:	Colorectal cancer Flow cytometry PD-L1 CD326 (EpCAM) Epithelial mesenchymal transition (EMT)
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2405844020327225
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!