Splenectomy has opposite effects on the growth of primary compared with metastatic tumors in a murine colon cancer model

Abstract The spleen is a key source of circulating and tumor-infiltrating immune cells. However, the effect of splenectomy on tumor growth remains unclear. At 3 weeks after splenectomy, we subcutaneously injected LuM1 cells into BALB/c mice and evaluated the growth of primary tumors and lung metasta...

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Hlavní autoři:	Yuki Kaneko, Hideyo Miyato, Mineyuki Tojo, Yurie Futoh, Kazuya Takahashi, Yuki Kimura, Akira Saito, Hideyuki Ohzawa, Hironori Yamaguchi, Naohiro Sata, Joji Kitayama, Yoshinori Hosoya
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2024-02-01
Edice:	Scientific Reports
On-line přístup:	https://doi.org/10.1038/s41598-024-54768-5
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