Multiplexed MRM-based proteomics for identification of circulating proteins as biomarkers of cardiovascular damage progression associated with diabetes mellitus

Abstract Background Type 2 diabetes mellitus (T2DM) increases the risk of coronary heart disease (CHD) by 2–4 fold, and is associated with endothelial dysfunction, dyslipidaemia, insulin resistance, and chronic hyperglycaemia. The aim of this investigation was to assess, by a multimarker mass spectr...

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主要な著者:	Francesco Piarulli, Cristina Banfi, Eugenio Ragazzi, Erica Gianazza, Marco Munno, Massimo Carollo, Pietro Traldi, Annunziata Lapolla, Giovanni Sartore
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2024-01-01
シリーズ:	Cardiovascular Diabetology
主題:	Proteomics Blood proteins Diabetes mellitus Cardiovascular disease Mass spectrometry Multiple reaction monitoring
オンライン･アクセス:	https://doi.org/10.1186/s12933-024-02125-1
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