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Proteome profiling identifies circulating biomarkers associated with hepatic steatosis in subjects with Prader-Willi syndrome

IntroductionPrader-Willi syndrome (PWS) is a rare genetic disorder characterized by loss of expression of paternal chromosome 15q11.2-q13 genes. Individuals with PWS exhibit unique physical, endocrine, and metabolic traits associated with severe obesity. Identifying liver steatosis in PWS is challen...

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Principais autores: Devis Pascut, Pablo J. Giraudi, Cristina Banfi, Stefania Ghilardi, Claudio Tiribelli, Adele Bondesan, Diana Caroli, Alessandro Minocci, Graziano Grugni, Alessandro Sartorio
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2023-11-01
סדרה:Frontiers in Endocrinology
נושאים:
proteomics
proteome
circulating biomarkers
PWS
steatosis
cardiovascular
גישה מקוונת:https://www.frontiersin.org/articles/10.3389/fendo.2023.1254778/full
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