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HES1 protein oscillations are necessary for neural stem cells to exit from quiescence

Summary: Quiescence is a dynamic process of reversible cell cycle arrest. High-level persistent expression of the HES1 transcriptional repressor, which oscillates with an ultradian periodicity in proliferative neural stem cells (NSCs), is thought to mediate quiescence. However, it is not known wheth...

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Hauptverfasser: Elli Marinopoulou, Veronica Biga, Nitin Sabherwal, Anzy Miller, Jayni Desai, Antony D. Adamson, Nancy Papalopulu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2021-10-01
Schriftenreihe:iScience
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Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2589004221011664
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