HES1 protein oscillations are necessary for neural stem cells to exit from quiescence

Summary: Quiescence is a dynamic process of reversible cell cycle arrest. High-level persistent expression of the HES1 transcriptional repressor, which oscillates with an ultradian periodicity in proliferative neural stem cells (NSCs), is thought to mediate quiescence. However, it is not known wheth...

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Autors principals:	Elli Marinopoulou, Veronica Biga, Nitin Sabherwal, Anzy Miller, Jayni Desai, Antony D. Adamson, Nancy Papalopulu
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2021-10-01
Col·lecció:	iScience
Matèries:	molecular biology cell biology stem cells research
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2589004221011664
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