Inherent limitations of probabilistic models for protein-DNA binding specificity.
The specificities of transcription factors are most commonly represented with probabilistic models. These models provide a probability for each base occurring at each position within the binding site and the positions are assumed to contribute independently. The model is simple and intuitive and is...
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| Glavni autori: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science (PLoS)
2017-07-01
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| Serija: | PLoS Computational Biology |
| Online pristup: | http://europepmc.org/articles/PMC5521849?pdf=render |
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