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The GPCR Smoothened on cholinergic interneurons modulates dopamine-associated acetylcholine dynamics, learning, and effort management

Summary: The striatum is a hub for associative learning where fluctuations in dopamine (DA) and acetylcholine (ACh) regulate behavior. ACh is released by cholinergic interneurons (CIN), which integrate diverse inputs that contextualize DA signals and shape behavior. We previously observed that the G...

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書誌詳細
主要な著者: Santiago Uribe-Cano, Andreas H. Kottmann
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2026-05-01
シリーズ:iScience
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オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S2589004226006991
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