The GPCR Smoothened on cholinergic interneurons modulates dopamine-associated acetylcholine dynamics, learning, and effort management
Summary: The striatum is a hub for associative learning where fluctuations in dopamine (DA) and acetylcholine (ACh) regulate behavior. ACh is released by cholinergic interneurons (CIN), which integrate diverse inputs that contextualize DA signals and shape behavior. We previously observed that the G...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2026-05-01
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| Serie: | iScience |
| Soggetti: | |
| Accesso online: | http://www.sciencedirect.com/science/article/pii/S2589004226006991 |
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