Cell Cycle Arrest and Apoptosis-Inducing Ability of Benzimidazole Derivatives: Design, Synthesis, Docking, and Biological Evaluation

In the current study, new benzimidazole-based 1,3,4-oxadiazole derivatives have been synthesized and characterized by NMR, IR, MS, and elemental analysis. The final compounds were screened for cytotoxicity against MDA-MB-231, SKOV3, and A549 cell lines and EGFR for inhibitory activities. Compounds <...

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Principais autores:	Syed Nazreen, Abdulraheem S. A. Almalki, Serag Eldin I. Elbehairi, Ali A. Shati, Mohammad Y. Alfaifi, Ahmed A. Elhenawy, Nawaf I. Alsenani, Anas Alfarsi, Abdulrahman Alhadhrami, Esam A. Alqurashi, Mohammad Mahboob Alam
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2022-10-01
Series:	Molecules
Assuntos:	1,3,4-oxadiazole benzimidazole cell cycle arrest apoptosis docking
Acceso en liña:	https://www.mdpi.com/1420-3049/27/20/6899
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