Cell Cycle Arrest and Apoptosis-Inducing Ability of Benzimidazole Derivatives: Design, Synthesis, Docking, and Biological Evaluation

In the current study, new benzimidazole-based 1,3,4-oxadiazole derivatives have been synthesized and characterized by NMR, IR, MS, and elemental analysis. The final compounds were screened for cytotoxicity against MDA-MB-231, SKOV3, and A549 cell lines and EGFR for inhibitory activities. Compounds <...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Syed Nazreen, Abdulraheem S. A. Almalki, Serag Eldin I. Elbehairi, Ali A. Shati, Mohammad Y. Alfaifi, Ahmed A. Elhenawy, Nawaf I. Alsenani, Anas Alfarsi, Abdulrahman Alhadhrami, Esam A. Alqurashi, Mohammad Mahboob Alam
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2022-10-01
Serie:	Molecules
Soggetti:	1,3,4-oxadiazole benzimidazole cell cycle arrest apoptosis docking
Accesso online:	https://www.mdpi.com/1420-3049/27/20/6899
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!