Synthesis and Biological Evaluation of 1,2,3-Triazole Tethered Thymol-1,3,4-Oxadiazole Derivatives as Anticancer and Antimicrobial Agents

A library of 1,2,3-triazole-incorporated thymol-1,3,4-oxadiazole derivatives (<b>6</b>–<b>18</b>) hasbeen synthesized and tested for anticancer and antimicrobial activities. Compounds <b>7</b>, <b>8</b>, <b>9</b>, <b>10</b>, and <b>11</b> exhibited significant antiproliferative activity. Among these...

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Autores principales:	Abdulraheem S. A. Almalki, Syed Nazreen, Azizah M. Malebari, Nada M. Ali, Ahmed A. Elhenawy, Abdullah A. A. Alghamdi, Abrar Ahmad, Sulaiman Y. M. Alfaifi, Meshari A. Alsharif, Mohammad Mahboob Alam
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2021-08-01
Colección:	Pharmaceuticals
Materias:	thymol 1,2,3-triazole 1,3,4-oxadiazole cytotoxicity antimicrobial computational studies
Acceso en línea:	https://www.mdpi.com/1424-8247/14/9/866
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