Purification of Monoclonal Antibodies Using a Fiber Based Cation-Exchange Stationary Phase: Parameter Determination and Modeling

Monoclonal antibodies (mAb) currently dominate the market for protein therapeutics. Because chromatography unit operations are critical for the purification of therapeutic proteins, the process integration of novel chromatographic stationary phases, driven by the demand for more economic process sch...

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Detalhes bibliográficos

Principais autores:	Jan Schwellenbach, Steffen Zobel, Florian Taft, Louis Villain, Jochen Strube
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2016-10-01
coleção:	Bioengineering
Assuntos:	monoclonal antibodies downstream processing cation-exchange chromatography model simulation parameter determination
Acesso em linha:	http://www.mdpi.com/2306-5354/3/4/24
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