Purification of Monoclonal Antibodies Using a Fiber Based Cation-Exchange Stationary Phase: Parameter Determination and Modeling

Monoclonal antibodies (mAb) currently dominate the market for protein therapeutics. Because chromatography unit operations are critical for the purification of therapeutic proteins, the process integration of novel chromatographic stationary phases, driven by the demand for more economic process sch...

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Bibliografische Detailangaben

Hauptverfasser:	Jan Schwellenbach, Steffen Zobel, Florian Taft, Louis Villain, Jochen Strube
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2016-10-01
Schriftenreihe:	Bioengineering
Schlagworte:	monoclonal antibodies downstream processing cation-exchange chromatography model simulation parameter determination
Online-Zugang:	http://www.mdpi.com/2306-5354/3/4/24
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