Aggregation-prone GFAP mutation in Alexander disease validated using a zebrafish model
Abstract Background Alexander disease (AxD) is an astrogliopathy that predominantly affects the white matter of the central nervous system (CNS), and is caused by a mutation in the gene encoding the glial fibrillary acidic protein (GFAP), an intermediate filament primarily expressed in astrocytes an...
Guardat en:
| Autors principals: | , , , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BMC
2017-09-01
|
| Col·lecció: | BMC Neurology |
| Matèries: | |
| Accés en línia: | http://link.springer.com/article/10.1186/s12883-017-0938-7 |
| Etiquetes: |
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|