Aggregation-prone GFAP mutation in Alexander disease validated using a zebrafish model
Abstract Background Alexander disease (AxD) is an astrogliopathy that predominantly affects the white matter of the central nervous system (CNS), and is caused by a mutation in the gene encoding the glial fibrillary acidic protein (GFAP), an intermediate filament primarily expressed in astrocytes an...
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| Principais autores: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2017-09-01
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| Colecção: | BMC Neurology |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s12883-017-0938-7 |
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