Investigation of an oncolytic herpes simplex virus as a potential therapeutic agent for gastroenteropancreatic neuroendocrine neoplasms

Abstract Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) present unique challenges due to their heterogeneity and limited treatment options. Oncolytic virotherapy has emerged as a promising therapeutic for other NETs and thus, we sought to investigate the potential of an engineered oncolytic...

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Principais autores:	Colin H. Quinn, Janet R. Julson, Michael H. Erwin, Hooper R. Markert, Larua V. Bownes, Jerry E. Stewart, Sorina Shirley, Karina J. Yoon, Jamie M. Aye, James M. Markert, Elizabeth A. Beierle
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-04-01
coleção:	Scientific Reports
Assuntos:	Neuroendocrine tumors Oncolytic virus Patient derived xenografts Translational research
Acesso em linha:	https://doi.org/10.1038/s41598-025-98588-7
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