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Investigation of an oncolytic herpes simplex virus as a potential therapeutic agent for gastroenteropancreatic neuroendocrine neoplasms

Abstract Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) present unique challenges due to their heterogeneity and limited treatment options. Oncolytic virotherapy has emerged as a promising therapeutic for other NETs and thus, we sought to investigate the potential of an engineered oncolytic...

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Autors principals: Colin H. Quinn, Janet R. Julson, Michael H. Erwin, Hooper R. Markert, Larua V. Bownes, Jerry E. Stewart, Sorina Shirley, Karina J. Yoon, Jamie M. Aye, James M. Markert, Elizabeth A. Beierle
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2025-04-01
Col·lecció:Scientific Reports
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Accés en línia:https://doi.org/10.1038/s41598-025-98588-7
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