Correlations between pathogenic variants in DNA repair genes and anticancer treatment efficacy in stage IV non‐small cell lung cancer: A large real‐world cohort and review of the literature

Abstract Background Mutations in genes involved in DNA damage repair (DDR), a hallmark of cancer, are associated with increased cancer cell sensitivity to certain therapies. This study sought to evaluate the association of DDR pathogenic variants with treatment efficacy in patients with advanced non...

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Bibliografische gegevens

Hoofdauteurs:	Itamar Averbuch, Roi Tschernichovsky, Oded Icht, Daniel A. Goldstein, Raz Mutai, Elizabeth Dudnik, Ofer Rotem, Nir Peled, Aaron M. Allen, Smadar Laufer‐Geva, Yael Goldberg, Alona Zer
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Wiley 2023-06-01
Reeks:	Thoracic Cancer
Onderwerpen:	DNA damage repair mutations immunotherapy non‐small cell lung cancer platinum‐based chemotherapy radiotherapy
Online toegang:	https://doi.org/10.1111/1759-7714.14902
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