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Mast cell secretory granule fusion with amphisomes coordinates their homotypic fusion and release of exosomes

Summary: Secretory granule (SG) fusion is an intermediate step in SG biogenesis. However, the precise mechanism of this process is not completely understood. We show that Golgi-derived mast cell (MC) SGs enlarge through a mechanism that is dependent on phosphoinositide (PI) remodeling and fusion wit...

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-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Sewar Omari, Amit Roded, Maggie Eisenberg, Hydar Ali, Mitsunori Fukuda, Stephen J. Galli, Ronit Sagi-Eisenberg
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Elsevier 2024-07-01
Цуврал:Cell Reports
Нөхцлүүд:
Онлайн хандалт:http://www.sciencedirect.com/science/article/pii/S2211124724008118
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