RORα–GABP–TFAM axis alleviates myosteatosis with fatty atrophy through reinforcement of mitochondrial capacity

Abstract Background Fat infiltration in muscle, called ‘myosteatosis’, precedes muscle atrophy, which subsequently results in sarcopenia. Myosteatosis is frequently observed in patients with nonalcoholic fatty liver disease (NAFLD). We have previously reported that retinoic acid receptor‐related orp...

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Үндсэн зохиолчид:	Hyeon‐Ji Kim, Sang‐Heon Lee, Cheolhee Jeong, Yong‐Hyun Han, Mi‐Ock Lee
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Wiley 2024-04-01
Цуврал:	Journal of Cachexia, Sarcopenia and Muscle
Нөхцлүүд:	fatty atrophy mitochondrial biogenesis myosteatosis NAFLD RORα
Онлайн хандалт:	https://doi.org/10.1002/jcsm.13432
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!