RORα–GABP–TFAM axis alleviates myosteatosis with fatty atrophy through reinforcement of mitochondrial capacity

Abstract Background Fat infiltration in muscle, called ‘myosteatosis’, precedes muscle atrophy, which subsequently results in sarcopenia. Myosteatosis is frequently observed in patients with nonalcoholic fatty liver disease (NAFLD). We have previously reported that retinoic acid receptor‐related orp...

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Hlavní autoři:	Hyeon‐Ji Kim, Sang‐Heon Lee, Cheolhee Jeong, Yong‐Hyun Han, Mi‐Ock Lee
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2024-04-01
Edice:	Journal of Cachexia, Sarcopenia and Muscle
Témata:	fatty atrophy mitochondrial biogenesis myosteatosis NAFLD RORα
On-line přístup:	https://doi.org/10.1002/jcsm.13432
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