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Characterizing collaborative transcription regulation with a graph-based deep learning approach.

Human epigenome and transcription activities have been characterized by a number of sequence-based deep learning approaches which only utilize the DNA sequences. However, transcription factors interact with each other, and their collaborative regulatory activities go beyond the linear DNA sequence....

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Bibliographic Details
Main Authors: Zhenhao Zhang, Fan Feng, Jie Liu
Format: Artigo
Language:Inglês
Published: Public Library of Science (PLoS) 2022-06-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010162
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