MORC proteins regulate transcription factor binding by mediating chromatin compaction in active chromatin regions

Abstract Background The microrchidia (MORC) proteins are a family of evolutionarily conserved GHKL-type ATPases involved in chromatin compaction and gene silencing. Arabidopsis MORC proteins act in the RNA-directed DNA methylation (RdDM) pathway, where they act as molecular tethers to ensure the eff...

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Bibliografische Detailangaben

Hauptverfasser:	Zhenhui Zhong, Yan Xue, C. Jake Harris, Ming Wang, Zheng Li, Yunqing Ke, Mukun Liu, Jessica Zhou, Yasaman Jami-Alahmadi, Suhua Feng, James A. Wohlschlegel, Steven E. Jacobsen
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2023-04-01
Schriftenreihe:	Genome Biology
Schlagworte:	Microrchidia MORC Chromatin compaction TF binding Transcription regulation
Online-Zugang:	https://doi.org/10.1186/s13059-023-02939-4
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