Design, synthesis, and anti-Staphylococcus aureus evaluation of quinazolinone-based FabH inhibitors
Multidrug-resistant Staphylococcus aureus sparks global crisis and novel fatty acid synthesis enzyme FabH inhibitors could overcome resistance. Through rational design, we developed a series of quinazolinone-benzodioxin FabH inhibitors. The results showed that some of the newly synthesized compounds...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2025-11-01
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| Serie: | Results in Chemistry |
| Soggetti: | |
| Accesso online: | http://www.sciencedirect.com/science/article/pii/S2211715625008483 |
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