QR Kod

Tenascin‐C immobilizes infiltrating T lymphocytes through CXCL12 promoting breast cancer progression

Abstract Immune checkpoint therapy, where CD8 tumor infiltrating T lymphocytes (TIL) are reactivated, is a promising anti‐cancer treatment approach, yet with low response rates. The extracellular matrix, in particular tenascin‐C, may generate barriers for TIL. To investigate this possibility, we use...

Ful tanımlama

Kaydedildi:
Asıl Yazarlar: Devadarssen Murdamoothoo, Zhen Sun, Alev Yilmaz, Gilles Riegel, Chérine Abou‐Faycal, Claire Deligne, Ines Velazquez‐Quesada, William Erne, Marine Nascimento, Matthias Mörgelin, Gérard Cremel, Nicodème Paul, Raphael Carapito, Romain Veber, Hélène Dumortier, Jingping Yuan, Kim S Midwood, Thomas Loustau, Gertraud Orend
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer Nature 2021-05-01
Seri Bilgileri:EMBO Molecular Medicine
Konular:
CD8 tumor infiltrating lymphocytes
CXCL12
extracellular matrix
tenascin‐C
Tumor immune microenvironment
Online Erişim:https://doi.org/10.15252/emmm.202013270
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller