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Investigation of the structure-activity relationship at the N-terminal part of minigastrin analogs

Abstract Background Over the last years, several strategies have been reported to improve the metabolic stability of minigastrin analogs. However, currently applied compounds still reveal limited in vitro and in vivo stability. We thus performed a glycine scan at the N-terminus of DOTA-MGS5 (DOTA-d-...

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Bibliografische gegevens
Hoofdauteurs: Nadine Holzleitner, Thomas Günther, Amira Daoud-Gadieh, Constantin Lapa, Hans-Jürgen Wester
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: SpringerOpen 2023-07-01
Reeks:EJNMMI Research
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Online toegang:https://doi.org/10.1186/s13550-023-01016-y
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