Casein kinase 1 dynamics underlie substrate selectivity and the PER2 circadian phosphoswitch
Post-translational control of PERIOD stability by Casein Kinase 1δ and ε (CK1) plays a key regulatory role in metazoan circadian rhythms. Despite the deep evolutionary conservation of CK1 in eukaryotes, little is known about its regulation and the factors that influence substrate selectivity on func...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications Ltd
2020-02-01
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| Schriftenreihe: | eLife |
| Schlagworte: | |
| Online-Zugang: | https://elifesciences.org/articles/52343 |
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