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Single cell transcriptome amplification with MALBAC.

Recently, Multiple Annealing and Looping-Based Amplification Cycles (MALBAC) has been developed for whole genome amplification of an individual cell, relying on quasilinear instead of exponential amplification to achieve high coverage. Here we adapt MALBAC for single-cell transcriptome amplification...

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Detalles Bibliográficos
Autores principales: Alec R Chapman, Zi He, Sijia Lu, Jun Yong, Longzhi Tan, Fuchou Tang, X Sunney Xie
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2015-01-01
Colección:PLoS ONE
Acceso en línea:http://europepmc.org/articles/PMC4378937?pdf=render
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