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Single cell transcriptome amplification with MALBAC.

Recently, Multiple Annealing and Looping-Based Amplification Cycles (MALBAC) has been developed for whole genome amplification of an individual cell, relying on quasilinear instead of exponential amplification to achieve high coverage. Here we adapt MALBAC for single-cell transcriptome amplification...

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Autors principals: Alec R Chapman, Zi He, Sijia Lu, Jun Yong, Longzhi Tan, Fuchou Tang, X Sunney Xie
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2015-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC4378937?pdf=render
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