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Single cell transcriptome amplification with MALBAC.

Recently, Multiple Annealing and Looping-Based Amplification Cycles (MALBAC) has been developed for whole genome amplification of an individual cell, relying on quasilinear instead of exponential amplification to achieve high coverage. Here we adapt MALBAC for single-cell transcriptome amplification...

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Principais autores: Alec R Chapman, Zi He, Sijia Lu, Jun Yong, Longzhi Tan, Fuchou Tang, X Sunney Xie
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2015-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC4378937?pdf=render
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