Chlamydia trachomatis-containing vacuole serves as deubiquitination platform to stabilize Mcl-1 and to interfere with host defense

Obligate intracellular Chlamydia trachomatis replicate in a membrane-bound vacuole called inclusion, which serves as a signaling interface with the host cell. Here, we show that the chlamydial deubiquitinating enzyme (Cdu) 1 localizes in the inclusion membrane and faces the cytosol with the active d...

Whakaahuatanga katoa

Ngā taipitopito rārangi puna kōrero

Ngā kaituhi matua:	Annette Fischer, Kelly S Harrison, Yesid Ramirez, Daniela Auer, Suvagata Roy Chowdhury, Bhupesh K Prusty, Florian Sauer, Zoe Dimond, Caroline Kisker, P Scott Hefty, Thomas Rudel
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	eLife Sciences Publications Ltd 2017-03-01
Rangatū:	eLife
Ngā marau:	Chlamydia trachomatis deubiquitinase Mcl-1 cell-autonomous defense
Urunga tuihono:	https://elifesciences.org/articles/21465
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!