Côd QR

Systematic Comparison of CRISPR and shRNA Screens to Identify Essential Genes Using a Graph-Based Unsupervised Learning Model

Generally, essential genes identified using shRNA and CRISPR are not always the same, raising questions about the choice between these two screening platforms. To address this, we systematically compared the performance of CRISPR and shRNA to identify essential genes across different gene expression...

Disgrifiad llawn

Wedi'i Gadw mewn:
Prif Awduron: Yulian Ding, Connor Denomy, Andrew Freywald, Yi Pan, Franco J. Vizeacoumar, Frederick S. Vizeacoumar, Fang-Xiang Wu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI AG 2024-10-01
Cyfres:Cells
Pynciau:
CRISPR
shRNA
gene expression
essential gene
graph-based model
consensus maximization
Mynediad Ar-lein:https://www.mdpi.com/2073-4409/13/19/1653
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg