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Induction of chronic destructive arthritis in SCID mice by arthritogenic fibroblast-like synoviocytes derived from mice with antigen-induced arthritis

Abstract Background Fibroblast-like synoviocytes (FLSs) from patients with rheumatoid arthritis (RA) are autonomously activated to maintain inflammation and joint destruction in co-transplantation models. To elucidate inducing mechanisms involved in this altered behavior, the arthritogenic potential...

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Principais autores: Oliver Frey, Marion Hückel, Mieczyslaw Gajda, Peter K. Petrow, Rolf Bräuer
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2018-11-01
Serier:Arthritis Research & Therapy
Fag:
Arthritis
Synovial fibroblast
Joint destruction
Online adgang:http://link.springer.com/article/10.1186/s13075-018-1720-y
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