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Induction of chronic destructive arthritis in SCID mice by arthritogenic fibroblast-like synoviocytes derived from mice with antigen-induced arthritis

Abstract Background Fibroblast-like synoviocytes (FLSs) from patients with rheumatoid arthritis (RA) are autonomously activated to maintain inflammation and joint destruction in co-transplantation models. To elucidate inducing mechanisms involved in this altered behavior, the arthritogenic potential...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Oliver Frey, Marion Hückel, Mieczyslaw Gajda, Peter K. Petrow, Rolf Bräuer
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2018-11-01
Schriftenreihe:Arthritis Research & Therapy
Schlagworte:
Arthritis
Synovial fibroblast
Joint destruction
Online-Zugang:http://link.springer.com/article/10.1186/s13075-018-1720-y
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