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Astragalin attenuates caerulein-induced acute pancreatitis by targeting the NLRP3 signaling pathway and gut microbiota

Abstract Background Acute pancreatitis (AP) has caused great concern worldwide due to its serious threat to human health. Astragalin is a bioactive natural flavonoid compound with several pharmacological activities, but it remains unclear about its effect on AP. The objective of this experiment was...

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Principais autores: Yan Jia, Yuxin Shi, Jie Wang, Honghui Liu, Hanyue Wang, Yilin Huang, Ya Liu, Peiyan Chen, Jie Peng
פורמט: Artigo
שפה:Inglês
יצא לאור: SpringerOpen 2025-12-01
סדרה:Bioresources and Bioprocessing
נושאים:
Astragalin
Acute pancreatitis
Gut microbiota
Network pharmacology
NLRP3 signaling pathway
גישה מקוונת:https://doi.org/10.1186/s40643-025-00977-3
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